Hair loss in men is due to genetic predisposition, which includes 287 genes. This discovery may help scientists better understand the cause of male pattern baldness.
Hair loss in varying degrees, threatens most men struggle with baldness for centuries, and is yet a cure for baldness could not be found. Perhaps it is a recent discovery will help to find the exact cause of hair loss and, therefore, to approach the solution to the problem – scientists have identified 287 genes for baldness, according to a study published in the medical journal PLoS Genetics. These genetic variations can be used to predict the likelihood that a person will become bald.
Scientists from Edinburgh University (UK) conducted extensive genomic research and collected data on the genes of 52,000 men at the age from 49 to 60 years. In the end, scientists have identified 287 genes associated with severe hair loss.
The involved hair loss X chromosome
“We have identified hundreds of new genetic signals. Interestingly, in many genetic signals for the male models, baldness is associated with the X chromosome, which men inherit from their mothers, “said study leader, Saskia Hagenaars, postgraduate student, Centre of ageing and cognitive epidemiology at the University of Edinburgh.
In the study, researchers created a mathematical model, a formula by which they hope to predict the probability that a bald man. Despite the fact that the formula is far from accurate forecasts, it can help identify subgroups of the population for whom the risk of hair loss is much higher.
“We are still far from accurately predicting hair loss of an individual. The results of the study pave the way for a better understanding of the genetic causes of hair loss,” says the study’s lead author, Dr Riccardo Marioni, Centre of experimental medicine and genetics at the University of Edinburgh.