THE IMMUNE SYSTEM CAN AFFECT BRAIN FUNCTION

As you know, the immune system is necessary in order to protect the body from harmful bacteria and cells that cause cancer. But in addition has a large number of other functions. But the brain is separated from immune cells a kind of barrier, called the blood-brain. It aims to protect that body from toxic substances and pathologies. For this reason, for a long time it was believed that the brain and the peripheral immune system may not be connected. However, according to two studies that were conducted independently from each other, such a statement is refuted.

During the first scientific research, the scientists examined the blood of more than 500 volunteers for the presence of epigenetic profiles. The result was the information received regarding the fact that this profile was discovered, and it is directly linked with indicators such as the thickness of the cerebral cortex, especially in the area that is responsible for cognitive functions. In addition, it was found that these genes are directly involved in regulation of the immune function of the blood.

The second experiment involves the study of the genome in adults that are very well or very poorly remembered image of a negative character. It became known that the gene TROVE2, whose place in the formation of immune abnormalities has not been studied, affected the ability of study participants to memorize a fairly large number of negative images on the background that the shared memory features remained unchanged. In addition, this gene is responsible for the high activity of those brain areas in which the process of memorizing emotional experiences.

From the information obtained in the course of such studies it became clear that the structure of the brain, namely, memory is very much linked with the genes that regulate the immune system. This implies that drugs that affect the human immune system, can be useful in the treatment of diseases that affect the brain.